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For more than 70 years, Takeda has supplied vaccines to protect the health of people in Japan. Today, Takeda’s global vaccine business is applying innovation to tackle some of the world’s most challenging infectious diseases, such as dengue, COVID-19, pandemic influenza and Zika.

Therapeutic Focus - Vaccines | Takeda Pharmaceuticals

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For more than 70 years, we have supplied routine vaccines to protect the health of people in Japan including measles, rubella, and mumps. Today, we’re expanding our global vaccine business by applying innovation to tackle some of the world’s most challenging infectious diseases, such as dengue, COVID-19, pandemic influenza and Zika. 

Our team brings an outstanding track record and a wealth of knowledge in global vaccine development and manufacturing to advance a pipeline of vaccines to address some of the most pressing public health needs. 

Our mission is to develop and deliver innovative vaccines that tackle some of the toughest problems in public health and improve the lives of people around the world.


### Dengue

* A mosquito-borne viral disease that spreads rapidly around the world.4

* Estimated that half of the world's population is at risk of contracting the disease.4

### COVID-19

* Caused by a new coronavirus, SARS-CoV-2, first identified in December of 2019.5

* COVID-19 cases have been identified across all seven continents.6

### Zika

* Spread by the bite of an infected mosquito or passed from a pregnant woman to her fetus.7

* Has impacted 89 countries and territories.8

### Pandemic Influenza

* Influenza viruses are constantly changing, making it possible for them to infect people and easily spread.9

* Last four pandemics killed approximately 50-100 million (1918), 1.1 million (1957), 1 million (1968) and 0.2-0.6 million (2009) people.10,11,12,13

## Disease areas



* Vaccines prevent 3.5 to 5 million deaths each year and have transformed global public health.1

* Vaccines are one of the most cost-effective ways to save lives.2

* 51 million deaths can be prevented through immunization between 2021 and 2030.3

## The value of vaccination



## Educational resources

#### TIDES: Takeda’s Pivotal Phase 3 Dengue Clinical Trial



http://assets-dam.sdachurchsierraleone.org/raw/upload/v1668754472/legacy-dotcom/siteassets/system/what-we-do/areas-of-focus/vaccines/info/tides-fact-sheet.pdf

world map with endemic countries highlighted in red and connecting lines to non-endemic countries

#### Dengue in Non-Endemic Countries



http://assets-dam.sdachurchsierraleone.org/image/upload/v1678725697/Global/Areas%20of%20focus/Vaccines/Dengue_in_Non-Endemic_Counties_Fact_Sheet.pdf

#### Behind Vaccine Development: The Clinical Trial Process



http://assets-dam.sdachurchsierraleone.org/raw/upload/v1668754476/legacy-dotcom/siteassets/system/what-we-do/areas-of-focus/vaccines/info/behind-vaccine-development-the-clinical-trial-process-infographic.pdf

#### Dengue in Endemic Countries



http://assets-dam.sdachurchsierraleone.org/image/upload/v1678725698/Global/Areas%20of%20focus/Vaccines/Dengue_in_Endemic_Countries_Fact_Sheet.pdf

## Resources



### Videos

Learn more about the global burden of dengue on [our video channel](http://youtube.com/playlist?list=PLdEbUoUDW_51Vv9y22KiZK1s0EG1u-RdW\&si=QY6jAOzIEV3o2p5Q).


## Our Stories



Young victims of an outbreak of dengue fever crowd the children's ward of the government-run Quirino Memorial Hospital in Manila

What drives our dengue researchers? Seeing the disease up close


/our-impact/our-stories/what-drives-our-dengue-researchers/

A father's experience with dengue


/our-impact/our-stories/a-father-experience-with-dengue/

## References

1.  World Health Organization. Vaccines and Immunization. Retrieved May 25, 2022.

2.  GAVI. Cost-effective. February 2020. Retrieved January 13, 2023.

3.  CDC. Global Immunization. September 2022, Retrieved February 28, 2023

4.  World Health Organization. Dengue and Severe Dengue. World Health Organization. http://www.who.int/en/news-room/fact-sheets/detail/dengue-and-severe-dengue. Published June 23, 2020.

5.  World Health Organization. Coronavirus disease (COVID-19). October 2020. Retrieved September 23, 2021.

6.  World Health Organization. WHO Coronavirus (COVID-19) Dashboard. September 2021. Retrieved September 23, 2021.

7.  World Health Organization. Zika Virus. World Health Organization. from http://www.who.int/news-room/fact-sheets/detail/zika-virus. Published July 20, 2018.

8.  World Health Organization. Zika epidemiology update. February 2022. Retrieved January 13, 2023.

9.  Centers for Disease Control and Prevention. Past Pandemics. August 2018. Retrieved September 23, 2021.

10. Centers for Disease Control and Prevention. 1918 Pandemic (H1N1 virus). June 2019. Retrieved September 23, 2021.

11. Centers for Disease Control and Prevention. 1957-1958 Pandemic (H2N2 virus). January 2019. Retrieved September 23, 2021.

12. Centers for Disease Control and Prevention. 1968 Pandemic (H3N2 virus). January 2019. Retrieved September 23, 2021.

13. Centers for Disease Control and Prevention. 2009 H1N1 Pandemic (H1N1pdm09 virus). June 2019. Retrieved September 23, 2021.

